“In silico screening by AlphaFold2 program revealed the potential binding partners of nuage-localizing proteins and piRNA-related proteins”

The research group of Shinichi Kawaguchi, an assistant professor at the Graduate School of Frontier Biosciences at the University of Osaka, used AlphaFold, an AI program developed and published by DeepMind in the United States, to predict the binding between proteins on a large scale on a supercomputer and found a new pair of binding proteins.

In this study, Date and Soga supported to parallelization of AlphaFold2 on Supercomputer system SQUID.

The research paper of this study were accepted in the international scientific journal "eLife" and released in a press release.

”Kawaguchi Shinichi, Xu Xin, Soga Takashi, Yamaguchi Kenta, Kawasaki Ryuuya, Shimouchi Ryota, Date Susumu,

and Kai Toshie, “In silico screening by AlphaFold2 program revealed the potential binding partners of nuage-localizing

proteins and piRNA-related proteins”, eLife, April 2025 [DOI: https://doi.org/10.7554/eLife.101967].”